The CRISPR-Cas9 system has revolutionized genetic engineering. This groundbreaking discovery by scientists Jennifer Doudna and Emmanuelle Charpentier has brought medical research light-years closer to finding a cure for many diseases, including sickle cell anemia, HIV, cancer, Huntington’s disease and more.

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To make efficient and reliable ways to make precise, targeted changes to the genome of living cells is long sought goal for medical research. And recently, a new tool based on a bacterial CRISPR-associated protein-9 nuclease (Cas9) from Streptococcus pyogenes has made significant progress.